Study show that metabolism and stress are contributing factors in early brain programming. A collaboration between the University of Amsterdam, University Medical Centre Groningen and the Academic Medical Center, has found a micronutrient blend of methionine and B vitamins led to a degree of neuroprotection when given to young mice.
The researchers began by inducing stress in female mice by restricting the amount of material available in which to build nests. This restricted the amount of time spent with their offspring. Half the group of stressed mice were given a nutrient supplement of vitamins B6, B9 and B12 and the related amino acid methionine. The study found that offspring produced from the stressed mothers given the supplementation exhibited higher methionine levels in the brain and a lower hormonal stress response.
This study is impactful as "it enables researchers to look in a targeted way for nutritional interventions for children who are growing up in stressful circumstances, for example babies that have to undergo long-term hospital stays", highlighted Dr. Aniko Korosi, co-author of the study and assistant professor at the University of Amsterdam.
*The above information was adapted from Early Life Nutrition Builds Brain Resilience to Extreme Stress By. Will Chu